Small Molecule/Molecular Probe Synthesis

The Synthetic Chemical Biology (SBC) core assists investigators with small molecule synthesis and can provide design and synthesis of molecular probes

The SCB core assists investigators with novel and commercially unavailable small molecule synthesis.  Staff at the SCB can perform complex multi step organic synthesis in mg to multi gram scale. The SCB core can assist in structure activity relationship studies for hits obtained from high throughput screening campaigns, scale up of molecule of interest, intermediates, controls etc.

For investigators interested in chemical biology, the SCB core also provides design and synthesis of molecular probes. A major focus is to assist investigators that wish to create and study fluorescent molecules in biological systems. We offer custom synthesis of fluorescent small molecules, peptides, and other molecular probes.

Researcher giving explanations to a laboratory assistant in a laboratory